220 Lives Are Lost to Overdose Every Day
Overdose Lifeline offers support, harm reduction, and education so individuals and families never face addiction alone.
We wrote a book.
Together Apart and the Love That Remains is a collection of stories from families who have lost someone to overdose.
If you’ve ever loved someone battling addiction, felt helpless, or wondered how to keep showing up, these stories are for you.

Substance Use Disorder Help When and Where It’s Needed
Today, Americans are more likely to die due to an overdose than they are from cars and guns. Overdose Lifeline’s objective is not only to increase access to overdose prevention and education services but also to remove the stigma of addiction and provide proper care for those at risk.
Overdose due to opioid use has become a leading cause of death in the US. Today, Americans are more likely to die due to an overdose than they are from cars and guns. Yet services, specifically those aimed at overdose prevention and substance use help, do not meet the growing opioid crisis.
Overdose Lifeline’s objective is not only to increase access to overdose prevention and education services but also to remove the stigma of addiction and provide proper care and access to treatment for those at risk.
Learn more about Substance Use Disorder and the overdose epidemic.
Why Overdose Prevention Matters
1 in 4
noncancer opioid users struggle with addiction
100,000+
overdose deaths in the US were estimated to have occurred in 2021
90 percent
of addictions have been proven to originate during the teenage years
Substance Use Disorder Prevention and Education Programs
Overdose Lifeline offers evidence-based programs for developing overdose prevention strategies that seek to address underlying problems, raise awareness and develop crucial support networks. Learn about some of our main programs and how to take part below.
MATE Act Approved CE Courses
Fulfill your DEA MATE Act 8-hour training with Overdose Lifeline’s ACCME and ANCC accredited on-demand online courses.

Increasing Access to Overdose Prevention
Equal access to naloxone is a key step in fighting the opioid epidemic, providing lifesaving treatment for those who experience an overdose. Overdose Lifeline aims to reduce barriers to naloxone access.
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ODL Events & Trainings
Essential News Posts

The Mother’s Day No One Talks About
International Bereaved Mother’s Day is a chance to honor mothers whose children have died. This post explores what that loss really looks like, why it’s so often misunderstood, and a few meaningful ways you can show up for a bereaved mother this Mother’s Day.
Overdose Lifeline Fundraiser Raises Over $38,000 for Recovery Programs
This year’s Freedom to Rise Breakfast raised over $38,000 for Overdose Lifeline’s family-serving recovery programs, showing what a community can accomplish when it shows up with compassion.

From Caution to Advocacy: Senator Brett Clark on Saving Lives with Naloxone
From skepticism to advocacy, Senator Brett Clark shares how firsthand experience with naloxone reshaped his views—and why harm reduction tools are critical in saving lives across Indiana communities.
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