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How to Administer Naloxone

Naloxone For the Public


Although traditionally naloxone was administered only by emergency response personnel, today it can be administered by minimally trained laypeople. Overdose Lifeline is registered to provide naloxone (Narcan™) kits, servicing a limited number of communities through donations and sponsorships. 

Naloxone Delivery Devices



EVZIO is a one-time auto-injector designed to be easy to use. EVZIO is to be used on the outer thigh, through clothing, when needed.



Intramuscular naloxone comes packaged in single and multi-dose forms.


Amphastar with MAD Atomizer

Most pharmacies carry the Amphastar brand of intranasal naloxone, which along with a MAD atomizer will convert the liquid to a nasal spray.


Narcan® Nasal Spray

Narcan® by Adapt Pharma is a newer formulation of intranasal naloxone. It requires no assembly which makes for easy administration.

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Administration Video Guides

Intranasal Adapt

Intranasal Amphastar

Intramuscular Syringe

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